The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 07, 2017

Filed:

Apr. 10, 2015
Applicants:

Merck Sharp & Dohme Corp., Rahway, NJ (US);

Mochida Pharmaceutical Co., Ltd., Tokyo, JP;

Inventors:

Isao Sakurada, Gotemba, JP;

Tomokazu Hirabayashi, Gotemba, JP;

Yoshitaka Maeda, Gotemba, JP;

Hiroshi Nagasue, Gotemba, JP;

Takashi Mizuno, Gotemba, JP;

Jiayi Xu, Marlboro, NJ (US);

Ting Zhang, Princeton Junction, NJ (US);

Cameron Smith, Montgomery Village, MD (US);

Dann Parker, Cranford, NJ (US);

Assignees:
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/501 (2006.01); A61K 31/439 (2006.01); C07D 413/14 (2006.01); C07D 261/20 (2006.01); C07D 413/04 (2006.01); C07D 498/04 (2006.01); C07D 209/52 (2006.01); C07D 519/00 (2006.01); A61K 31/444 (2006.01); A61K 31/506 (2006.01); A61K 45/06 (2006.01);
U.S. Cl.
CPC ...
A61K 31/439 (2013.01); A61K 31/444 (2013.01); A61K 31/501 (2013.01); A61K 31/506 (2013.01); A61K 45/06 (2013.01); C07D 209/52 (2013.01); C07D 261/20 (2013.01); C07D 413/04 (2013.01); C07D 413/14 (2013.01); C07D 498/04 (2013.01); C07D 519/00 (2013.01);
Abstract

In its many embodiments, the present invention provides a novel class of benzamide compounds represented by Formula (I) or pharmaceutically acceptable salts or solvates thereof, or pharmaceutical compositions comprising one or more said compounds or pharmaceutically acceptable salts or solvates thereof, and methods for using said compounds or pharmaceutically acceptable salts or solvates thereof for treating or preventing a thromboses, embolisms, hypercoagulability or fibrotic changes.


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