The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 07, 2017
Filed:
Nov. 28, 2011
Viness Pillay, Gauteng, ZA;
Rubina Perveen Shaikh, Gauteng, ZA;
Yahya Essop Choonara, Gauteng, ZA;
Lisa Claire Du Toit, Gauteng, ZA;
Viness Pillay, Gauteng, ZA;
Rubina Perveen Shaikh, Gauteng, ZA;
Yahya Essop Choonara, Gauteng, ZA;
Lisa Claire Du Toit, Gauteng, ZA;
UNIVERSITY OF THE WITWATERSRAND, JOHANNESBURG, Johannesburg Gauteng, ZA;
Abstract
A pH responsive and mucoadhesive pharmaceutical dosage form for the release of a pharmaceutically active agent is described. The dosage form includes a mucoadhesive layer for site-specific mucoadhesion, a water-insoluble outer layer, and an intermediate layer including one or more pharmaceutically active agents for site-specific delivery. The different membranous layers perform different functions in order to create a drug delivery system which is able to deliver a drug to a specific site, for a particular period of time and with a specific drug release pattern. The dosage form can have two or more intermediate layers, each layer comprising an active agent. The mucoadhesive layer can also include an active agents. The dosage form is preferably an oral or buccal delivery form for release of the active agent into the gastro intestinal tract. The intermediate layer can be an electrospun fibrous membrane layer containing the active agent.