The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 31, 2017

Filed:

Oct. 28, 2014
Applicant:

Rutgers, the State University of New Jersey, New Brunswick, NJ (US);

Inventors:

John M. Akudugu, Bellville, ZA;

Venkata S. Neti, Lake Hiawatha, NJ (US);

Roger W. Howell, Millington, NJ (US);

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
G01N 33/60 (2006.01); G01N 33/50 (2006.01); A61K 31/704 (2006.01); A61K 51/04 (2006.01); A61K 51/10 (2006.01);
U.S. Cl.
CPC ...
G01N 33/60 (2013.01); A61K 31/704 (2013.01); A61K 51/0402 (2013.01); A61K 51/1051 (2013.01); G01N 33/5008 (2013.01); G01N 33/5011 (2013.01);
Abstract

Disclosed is a method for predicting the optimal amounts of radiopharmaceutical and/or chemotherapy agents to administer to a patient, by determining the level of saturation of the therapeutic agents in the patient's cells. The method comprises measuring cellular incorporation of the candidate therapeutic agents in a target cell population on a cell-by-cell basis. The method is able to identify an optimal cocktail of therapeutic agents for treatment of a disease. A method of high-throughput drug discovery incorporating this method, and a 2-stage targeting method of treating a disease using this method are also disclosed.


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