The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 31, 2017

Filed:

Aug. 06, 2010
Applicants:

Guanbin Zhang, Beijing, CN;

Guangxin Xiang, Beijing, CN;

Wanli Xing, Beijing, CN;

Jing Cheng, Beijing, CN;

Inventors:

Guanbin Zhang, Beijing, CN;

Guangxin Xiang, Beijing, CN;

Wanli Xing, Beijing, CN;

Jing Cheng, Beijing, CN;

Assignees:

Tsinghua University, Beijing, CN;

CapitalBio Corporation, Beijing, CN;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12Q 1/68 (2006.01); C40B 20/02 (2006.01);
U.S. Cl.
CPC ...
C12Q 1/6837 (2013.01); C12Q 2563/143 (2013.01); C12Q 2563/149 (2013.01); C12Q 2563/155 (2013.01);
Abstract

A microarray-based assay is provided, which is used for analyzing molecular interactions, including polynucleotides, polypeptides, antibodies, small molecule compounds, peptides and carbohydrates. Such method comprises coupling a target molecule to a particle and then binding to a probe molecule on microarray. In particular, multiplexed genetic analysis of nucleic acid fragments can be implemented. Specific genes, single nucleotide polymorphisms or gene mutations, such as deletions, insertions, and indels, can be identified. Coupled with microarray, the particles, themselves or further modified, facilitate the detection of results with non-expensive devices or even naked eyes. This technology enables the detection and interpretation of molecular interactions in an efficient and cost effective way.


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