The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 31, 2017
Filed:
Jul. 07, 2014
Applicant:
Daiichi Sankyo Company, Limited, Tokyo, JP;
Inventors:
Makoto Koizumi, Tokyo, JP;
Yoshiyuki Onishi, Tokyo, JP;
Takako Niwa, Tokyo, JP;
Masakazu Tamura, Tokyo, JP;
Yuji Kasuya, Tokyo, JP;
Assignee:
DAIICHI SANKYO COMPANY, LIMITED, Tokyo, JP;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 15/113 (2010.01); A61K 31/7088 (2006.01); A61K 31/713 (2006.01); C07C 219/16 (2006.01); C07D 211/22 (2006.01); C07D 211/46 (2006.01); A61K 47/48 (2006.01); A61K 9/127 (2006.01); C12N 15/11 (2006.01); A61K 9/10 (2006.01); A61K 47/18 (2017.01); A61K 47/22 (2006.01); A61K 47/28 (2006.01); A61K 47/44 (2017.01); A61K 48/00 (2006.01);
U.S. Cl.
CPC ...
C12N 15/113 (2013.01); A61K 9/10 (2013.01); A61K 9/127 (2013.01); A61K 9/1271 (2013.01); A61K 9/1272 (2013.01); A61K 31/7088 (2013.01); A61K 31/713 (2013.01); A61K 47/18 (2013.01); A61K 47/22 (2013.01); A61K 47/28 (2013.01); A61K 47/44 (2013.01); A61K 47/48046 (2013.01); A61K 48/005 (2013.01); A61K 48/0008 (2013.01); C07C 219/16 (2013.01); C07D 211/22 (2013.01); C07D 211/46 (2013.01); C12N 15/111 (2013.01); C12N 2310/14 (2013.01); C12N 2320/32 (2013.01);
Abstract
The present invention provides a compound represented by the formula (Ia) as a novel cationic lipid that forms a lipid particle and also provides a lipid particle comprising the compound. The present invention further provides a nucleic acid lipid particle containing the lipid particle, and a pharmaceutical composition containing the nucleic acid lipid particle as an active ingredient.