The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 31, 2017
Filed:
May. 25, 2012
Christian Degering, Erkrath, DE;
Thorsten Eggert, Hattingen, DE;
Stefan Evers, Mettmann, DE;
Karl-heinz Maurer, Erkrath, DE;
Johannes Bongaerts, Dormagen, DE;
Christian Degering, Erkrath, DE;
Thorsten Eggert, Hattingen, DE;
Stefan Evers, Mettmann, DE;
Karl-Heinz Maurer, Erkrath, DE;
Johannes Bongaerts, Dormagen, DE;
BASF SE, Ludwigshafen, DE;
Abstract
The aim of the invention is to improve the secretion of a protein from a host cell in order to increase the product yield of protein in a fermentation process. This is achieved by an expression vector comprising a promoter sequence and a nucleic acid sequence that codes for a protein. The protein comprises a signal peptide and an additional amino acid sequence, and the signal peptide comprises an amino acid sequence that is at least 80% identical to the amino acid sequence specified SEQ ID NO: 2, at least 80% identical to the amino acid sequence specified in SEQ ID NO: 4, at least 80% identical to the amino acid sequence specified in SEQ ID NO: 6, or the signal peptide comprises an amino acid sequence that is structurally homologous to at least one of said sequences.