The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 31, 2017

Filed:

Sep. 04, 2014
Applicant:

Leibniz-institut Fur Pflanzenbiochemie Stiftung Des Offentlichen Rechts, Halle (Saale), DE;

Inventors:

Martin Dippe, Halle, DE;

Wolfgang Brandt, Halle, DE;

Ludger A. Wessjohann, Halle, DE;

Hannes Rost, Halle, DE;

Andrea Porzel, Halle, DE;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 9/12 (2006.01); C12N 9/10 (2006.01); C12P 19/40 (2006.01);
U.S. Cl.
CPC ...
C12N 9/1085 (2013.01); C12P 19/40 (2013.01); C12Y 205/01006 (2013.01);
Abstract

The present invention relates to isolated polypeptides that are derived from wildtypeS-Adenosylmethionine (SAM) synthase or from a biologically active fragment thereof, wherein said isolated polypeptides comprise an amino acid sequence that, in relation to the amino acid sequence of said wildtypeSAM synthase or of the biologically active fragment thereof, comprises at least one amino acid substitution, selected from the group consisting of amino acid substitutions at positions I317 and I105. The present invention further relates to respective isolated nucleic acids, vectors, host cells, uses and methods for the production of SAM derivatives.


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