The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 31, 2017

Filed:

Jul. 25, 2012
Applicant:

Melissa K. Carpenter, Castro Valley, CA (US);

Inventor:

Melissa K. Carpenter, Castro Valley, CA (US);

Assignee:

Asterias Biotherapeutics, Inc., Fremont, CA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 5/0735 (2010.01); C12N 5/0793 (2010.01); C12N 5/079 (2010.01); C12N 5/0797 (2010.01); C12Q 1/68 (2006.01); A61K 35/12 (2015.01);
U.S. Cl.
CPC ...
C12N 5/0618 (2013.01); C12N 5/0623 (2013.01); C12Q 1/6881 (2013.01); A61K 35/12 (2013.01); C12N 2501/01 (2013.01); C12N 2501/105 (2013.01); C12N 2501/11 (2013.01); C12N 2501/115 (2013.01); C12N 2501/119 (2013.01); C12N 2501/13 (2013.01); C12N 2501/135 (2013.01); C12N 2503/02 (2013.01); C12N 2506/02 (2013.01); C12N 2510/00 (2013.01); C12Q 2600/158 (2013.01);
Abstract

This invention provides populations of neural progenitor cells, differentiated neurons, glial cells, and astrocytes. The populations are obtained by culturing stem cell populations (such as embryonic stem cells) in a cocktail of growth conditions that initiates differentiation, and establishes the neural progenitor population. The progenitors can be further differentiated in culture into a variety of different neural phenotypes, including dopaminergic neurons. The differentiated cell populations or the neural progenitors can be generated in large quantities for use in drug screening and the treatment of neurological disorders.


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