The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 31, 2017

Filed:

Apr. 23, 2012
Applicants:

Michael Thormann, Martinsried, DE;

Andreas Treml, Martinsried, DE;

Michael Almstetter, Martinsried, DE;

Nadine Traube, Martinsried, DE;

Inventors:

Michael Thormann, Martinsried, DE;

Andreas Treml, Martinsried, DE;

Michael Almstetter, Martinsried, DE;

Nadine Traube, Martinsried, DE;

Assignee:

ORIGENIS GMBH, Martinsreid, DE;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 487/04 (2006.01); A61K 31/519 (2006.01); A61P 29/00 (2006.01); A61P 11/06 (2006.01); A61P 37/08 (2006.01); A61P 27/02 (2006.01); A61P 17/04 (2006.01); A61P 37/06 (2006.01); A61P 35/02 (2006.01); A61P 35/04 (2006.01); A61P 35/00 (2006.01); C07D 519/00 (2006.01);
U.S. Cl.
CPC ...
C07D 487/04 (2013.01); C07D 519/00 (2013.01);
Abstract

The present invention relates to novel compounds of formula (I) that are capable of inhibiting one or more kinases, especially SYK (Spleen Tyrosine Kinase), LRRK2 (Leucine-rich repeat kinase 2) and/or MYLK (Myosin light chain kinase) or mutants thereof. The compounds find applications in the treatment of a variety of diseases. These diseases include autoimmune diseases, inflammatory diseases, bone diseases, metabolic diseases, neurological and neurodegenerative diseases, cancer, cardiovascular diseases, allergies, asthma, alzheimer's disease, parkinson's disease, skin disorders, eye diseases, infectious diseases and hormone-related diseases.


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