The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 31, 2017

Filed:

Jul. 29, 2016
Applicants:

The Regents of the University of Michigan, Ann Arbor, MI (US);

The Cleveland Clinic Foundation, Cleveland, OH (US);

Inventors:

William H. Fissell, Brecksville, OH (US);

Shuvo Roy, San Francisco, CA (US);

Aaron Fleischman, Beachwood, OH (US);

Kenneth G. Goldman, Olmsted Township, OH (US);

Assignees:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61M 1/16 (2006.01); B01D 61/18 (2006.01); A61B 5/145 (2006.01); B01D 61/14 (2006.01); B01D 61/20 (2006.01); B01D 67/00 (2006.01); A61M 1/26 (2006.01); G01N 1/40 (2006.01);
U.S. Cl.
CPC ...
B01D 61/145 (2013.01); A61B 5/14532 (2013.01); A61M 1/1623 (2014.02); A61M 1/267 (2014.02); B01D 61/18 (2013.01); B01D 61/20 (2013.01); B01D 67/0034 (2013.01); B01D 67/0062 (2013.01); B01D 67/0088 (2013.01); G01N 1/4077 (2013.01); B01D 2257/70 (2013.01); B01D 2313/243 (2013.01); B01D 2321/22 (2013.01); B01D 2325/028 (2013.01); G01N 2001/4088 (2013.01);
Abstract

The present invention relates to ultrafiltration. In particular, the present invention provides nanoporous membranes having pores for generating in vitro and in vivo ultrafiltrate, devices and bioartificial organs utilizing such nanoporous membranes, and related methods (e.g., diagnostic methods, research methods, drug screening). The present invention further provides nanoporous membranes configured to avoid protein fouling with, for example, a polyethylene glycol surface coating.


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