The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 31, 2017
Filed:
Aug. 22, 2014
The University of Tokyo, Tokyo, JP;
Kazunori Kataoka, Tokyo, JP;
Nobuhiro Nishiyama, Tokyo, JP;
Horacio Cabral, Tokyo, JP;
Peng Mi, Tokyo, JP;
Akihiro Kishimura, Tokyo, JP;
Yutaka Miura, Tokyo, JP;
Ichio Aoki, Chiba, JP;
Daisuke Kokuryo, Chiba, JP;
Tsuneo Saga, Chiba, JP;
THE UNIVERSITY OF TOKYO, Tokyo, JP;
Abstract
The present invention provides a safe polymer nanoparticle composite with few side effects, and an MRI contrast agent incorporating said polymer nanoparticle composite. The polymer nanoparticle composite is capable of specifically accumulating on a tumor tissue to selectively extract the tissue, exhibiting high contrast even when used in small amounts, and enabling imaging over prolonged periods of time. This polymer nanoparticle composite is characterized by containing a block copolymer that includes a non-charged hydrophilic polymer chain segment and an anionic polymer chain segment, and MnCaP.