The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 31, 2017
Filed:
Aug. 02, 2012
Douglas R. Spitz, Iowa City, IA (US);
Michael K. Schultz, Iowa City, IA (US);
Kyle Kloepping, Iowa City, IA (US);
Yueming Zhu, Iowa City, IA (US);
Nukhet Aykin-burns, Iowa City, IA (US);
Max S. Wicha, Ann Arbor, MI (US);
Douglas R. Spitz, Iowa City, IA (US);
Michael K. Schultz, Iowa City, IA (US);
Kyle Kloepping, Iowa City, IA (US);
Yueming Zhu, Iowa City, IA (US);
Nukhet Aykin-Burns, Iowa City, IA (US);
Max S. Wicha, Ann Arbor, MI (US);
UNIVERSITY OF IOWA RESEARCH FOUNDATION, Iowa City, IA (US);
REGENTS OF THE UNIVERSITY OF MICHIGAN, Ann Arbor, MI (US);
Abstract
The invention provides compositions and methods to treat cancer with an agent that increases reactive oxygen species (ROS) levels in cancer cell mitochondria ('an XTPP agent') or a pharmaceutically acceptable salt thereof, an inhibitor of hydroperoxide metabolism and a pharmaceutically acceptable diluent or carrier.