The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 31, 2017

Filed:

Jan. 11, 2017
Applicant:

Intec Pharma Ltd., Jerusalem, IL;

Inventors:

Nadav Navon, Jerusalem, IL;

David Kirmayer, Jerusalem, IL;

Julia Shvetz, Jerusalem, IL;

Elena Kluev, Jerusalem, IL;

Eva Abramov, Jerusalem, IL;

Zeev Weiss, Jerusalem, IL;

Giora Carni, Jerusalem, IL;

Assignee:

INTEC PHARMA LTD., Jerusalem, IL;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 9/48 (2006.01); A61K 9/00 (2006.01); A61K 9/70 (2006.01); A61K 31/198 (2006.01);
U.S. Cl.
CPC ...
A61K 9/4808 (2013.01); A61K 9/0065 (2013.01); A61K 9/7007 (2013.01); A61K 31/198 (2013.01);
Abstract

The invention provides for the use of an accordion pill comprising levodopa for the treatment of symptoms of Parkinson's disease in a subject in need thereof over a 24 hour period, to be administered to the subject in a twice daily administration regimen, with an interval of about 8 to about 10 hours between the first dose and the second dose, and with an interval of about 14 to about 16 hours between the second dose and the first dose of the following day. The twice daily administration regimen provides a stable blood plasma level of levodopa in the subject after multiple administrations and is effective in treating the symptoms of Parkinson's disease over a 24 hour period.


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