The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 24, 2017

Filed:

Sep. 13, 2012
Applicants:

Jie He, Beijing, CN;

Fengwei Tan, Beijing, CN;

Zhaoli Chen, Beijing, CN;

Nan Sun, Beijing, CN;

Inventors:

Jie He, Beijing, CN;

Fengwei Tan, Beijing, CN;

Zhaoli Chen, Beijing, CN;

Nan Sun, Beijing, CN;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 15/113 (2010.01); G01N 33/574 (2006.01); C07K 16/40 (2006.01); C12Q 1/68 (2006.01);
U.S. Cl.
CPC ...
G01N 33/57423 (2013.01); C07K 16/40 (2013.01); C12N 15/113 (2013.01); C12Q 1/6886 (2013.01); C12N 2310/14 (2013.01); C12Q 2600/118 (2013.01); C12Q 2600/158 (2013.01); G01N 2333/904 (2013.01);
Abstract

The present invention relates to a method for diagnosing the lung cancers such as non small lung cancer in a subject by using isocitrate dehydrogenase 1 as a diagnostic biomarker. The present invention also relates to a method for predicting the prognosis of the lung cancers such as non small lung cancer in a subject by using isocitrate dehydrogenase 1 as a prognostic biomarker. The present invention further relates to a method to suppress proliferation of lung tumor cells in a subject, decrease growth of lung tumor cells in a subject, or improve survival of a subject with lung cancer by using isocitrate dehydrogenase 1 as a therapeutic target.


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