The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 24, 2017

Filed:

May. 03, 2013
Applicant:

The Regents of the University of Michigan, Ann Arbor, MI (US);

Inventors:

Brandon H. McNaughton, Ann Arbor, MI (US);

Paivo Kinnunen, Ann Arbor, MI (US);

John G. Younger, Ann Arbor, MI (US);

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
G01N 33/553 (2006.01); G01N 1/30 (2006.01); C12Q 1/68 (2006.01); G01N 33/543 (2006.01);
U.S. Cl.
CPC ...
G01N 1/30 (2013.01); C12Q 1/6804 (2013.01); C12Q 1/6816 (2013.01); G01N 33/54326 (2013.01); G01N 33/54366 (2013.01);
Abstract

Sandwich separation is based on forming a sandwich complex with a magnetic bead, buoyant bead, and a target. Once a sandwich formation is created, the sandwich can be separated using its dual physical properties, namely magnetism and buoyancy. Sandwich separation is highly specific, allows for removal of the beads that do not have any attached target, and reduces the number of background beads. Sandwich separation can also be used to allow for target detection in raw specimen. Also, improvement of detection capability is accomplished by performing AMBR measurements on a solid interface, where the rotational period speeds up and allows for dramatically reduced time-to-result.


Find Patent Forward Citations

Loading…