The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 24, 2017

Filed:

May. 23, 2016
Applicant:

The Regents of the University of California, Oakland, CA (US);

Inventors:

Mark A. Akeson, Santa Cruz, CA (US);

David W. Deamer, Santa Cruz, CA (US);

Roger Jinteh Arrigo Chen, Saratoga, CA (US);

Assignee:
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C12Q 1/68 (2006.01); G01N 33/487 (2006.01); C25B 3/10 (2006.01); C12Q 1/54 (2006.01); G01N 27/327 (2006.01); G01N 27/416 (2006.01);
U.S. Cl.
CPC ...
C12Q 1/6874 (2013.01); C12Q 1/54 (2013.01); C12Q 1/6869 (2013.01); C25B 3/10 (2013.01); G01N 27/3278 (2013.01); G01N 27/4166 (2013.01); G01N 33/48721 (2013.01);
Abstract

Devices and methods that can detect and control an individual polymer in a mixture is acted upon by another compound, for example, an enzyme, in a nanopore are provided. The devices and methods also determine (˜>50 Hz) the nucleotide base sequence of a polynucleotide under feedback control or using signals generated by the interactions between the polynucleotide and the nanopore. The invention is of particular use in the fields of molecular biology, structural biology, cell biology, molecular switches, molecular circuits, and molecular computational devices, and the manufacture thereof.


Find Patent Forward Citations

Loading…