The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 24, 2017
Filed:
Feb. 04, 2015
Applicant:
Institute of Microbiology, Chinese Academy of Sciences, Beijing, CN;
Inventors:
Tingyi Wen, Beijing, CN;
Xiuling Shang, Beijing, CN;
Yun Zhang, Beijing, CN;
Shuwen Liu, Beijing, CN;
Yong Liang, Beijing, CN;
Yu Zhang, Beijing, CN;
Assignee:
INSTITUTE OF MICROBIOLOGY, CHINESE ACADEMY OF SCIENCES, Beijing, CN;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12P 13/04 (2006.01); C12P 13/24 (2006.01); C12N 9/04 (2006.01); C12N 9/92 (2006.01); C12N 15/77 (2006.01);
U.S. Cl.
CPC ...
C12P 13/24 (2013.01); C12N 9/0006 (2013.01); C12N 9/92 (2013.01); C12N 15/77 (2013.01); C12Y 101/01043 (2013.01); C12Y 101/01049 (2013.01); C12Y 503/01009 (2013.01);
Abstract
The present invention relates to recombinant bacteria producing L-amino acid, in which the recombinant bacteria has reduced expression of the glucose-6-phosphate isomerase gene pgi and improved expression of the glucose-6-phosphate dehydrogenase gene -opcA than the starting bacteria, where the starting bacterium is a bacterial strain that can accumulate target amino acid(s) and preferably, the amino acid is L-histidine.