The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 24, 2017
Filed:
Jul. 28, 2016
Applicant:
Quark Pharmaceuticals, Inc., Fremont, CA (US);
Inventors:
Elena Feinstein, Rehovot, IL;
Svetlana Adamsky, Gedera, IL;
Sharon Avkin-Nachum, Nes Zionna, IL;
Hagar Kalinski, Rishon-Le-Zion, IL;
Igor Mett, Rehovot, IL;
Assignee:
Primary Examiner:
Int. Cl.
CPC ...
C12N 15/113 (2010.01);
U.S. Cl.
CPC ...
C12N 15/1138 (2013.01); C12N 2310/14 (2013.01); C12N 2310/317 (2013.01); C12N 2310/3183 (2013.01); C12N 2310/32 (2013.01); C12N 2320/51 (2013.01);
Abstract
Disclosed herein are double stranded nucleic acid molecules and pharmaceutical compositions comprising same useful in the treatment of, inter alia, acute and chronic inflammation, neuropathic pain, primary graft dysfunction (PGD) after lung transplantation in a subject in need thereof. The compounds are preferably chemically synthesized and modified dsRNA compounds, which down regulate or inhibit expression of Toll like receptor 4.