The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 24, 2017

Filed:

Aug. 08, 2012
Applicants:

Knut Pettersson, Göteborg, SE;

Ola Camber, Bromma, SE;

Dan Sexton, Melrose, MA (US);

Andrew E. Nixon, Hanover, MA (US);

Inventors:

Knut Pettersson, Göteborg, SE;

Ola Camber, Bromma, SE;

Dan Sexton, Melrose, MA (US);

Andrew E. Nixon, Hanover, MA (US);

Assignees:

ATHERA BIOTECHNOLOGIES AB, Stockholm, SE;

DYAX CORP., Burlington, MA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07K 16/44 (2006.01); C07K 16/18 (2006.01); A61K 39/00 (2006.01);
U.S. Cl.
CPC ...
C07K 16/44 (2013.01); C07K 16/18 (2013.01); A61K 2039/505 (2013.01); C07K 2317/21 (2013.01); C07K 2317/55 (2013.01); C07K 2317/565 (2013.01); C07K 2317/92 (2013.01);
Abstract

The present disclosure relates to an antibody or antibody fragment capable of binding to phosphorylcholine and/or a phosphorylcholine conjugate, wherein the antibody or antibody fragment comprises a variable heavy chain (VH) domain and/or a variable light chain (VL) domain, and wherein (a) the VH domain comprises complementarity determining regions (CDRs) selected from the group consisting of: a CDR1 sequence having identity to the sequence of SEQ ID NO: 7; a CDR2 sequence having identity to the sequence of SEQ ID NO: 8; and a CDR3 sequence having identity to the sequence of SEQ ID NO: 9 or 10; and/or (b) the VL domain comprises CDRs selected from the group consisting of: a CDR4 sequence having identity to the sequence of SEQ ID NO: 11; a CDR5 sequence having identity to the sequence of SEQ ID NO: 12; a CDR6 sequence having identity to the sequence of SEQ ID NO: 13.


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