The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 24, 2017
Filed:
Apr. 03, 2015
Applicant:
Omrix Biopharmaceuticals Ltd., Rehovot, IL;
Inventors:
Roni Mintz, Moshav Shafir, IL;
Oleg Belyaev, Barnaul, RU;
Israel Nur, Moshav Timmorim, IL;
Liliana Bar, Rehovot, IL;
Roberto Meidler, Rehovot, IL;
Assignee:
Omrix Biopharmaceuticals Ltd., Rehovot, IL;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07K 1/18 (2006.01); A61K 39/395 (2006.01); C07K 16/06 (2006.01); A61K 39/00 (2006.01);
U.S. Cl.
CPC ...
C07K 16/065 (2013.01); A61K 39/39591 (2013.01); C07K 1/18 (2013.01); A61K 2039/505 (2013.01); C07K 2317/10 (2013.01); Y10S 530/83 (2013.01); Y10S 530/831 (2013.01);
Abstract
The invention relates to an immunoglobulin composition reduced in thrombogenic agents and to methods for its preparation. One method comprises subjecting an immunoglobulin containing solution to a negative cation exchanger chromatography at a pH in the range of higher than 3.8 to equal to or lower than 5.3. The solution can also be subjected to a negative anion exchanger chromatography at a pH in the range of 7 to 8.2.