The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 24, 2017

Filed:

Dec. 04, 2015
Applicant:

Roche Diagnostics Operations, Inc., Indianapolis, IN (US);

Inventors:

Dieter Heindl, Munich, DE;

Joachim Hoenes, Zwingenberg, DE;

Carina Horn, Biblis, DE;

Thomas Meier, Munich, DE;

Wolfgang Petrich, Bad Schoenborn, DE;

Assignee:

Roche Diagnostics Operations, Inc., Indianapolis, IN (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07H 19/207 (2006.01); G01N 33/533 (2006.01); G01N 33/535 (2006.01); G01N 33/542 (2006.01); G01N 33/573 (2006.01); G01N 33/58 (2006.01); C12Q 1/26 (2006.01); G01N 21/64 (2006.01);
U.S. Cl.
CPC ...
C07H 19/207 (2013.01); C12Q 1/26 (2013.01); G01N 21/6428 (2013.01); G01N 33/533 (2013.01); G01N 33/535 (2013.01); G01N 33/542 (2013.01); G01N 33/5735 (2013.01); G01N 33/581 (2013.01); G01N 33/582 (2013.01); G01N 2201/062 (2013.01); G01N 2333/90248 (2013.01);
Abstract

The invention also relates to compounds, which are useful for intra-molecular fluorescence resonance energy transfer (FRET), comprising the oxidized form of a carbaNADH-based first fluorophore and a second fluorophore that is excitable at a wave-length of between 445 to 540 nm and that has an emission maximum of greater than 560 nm, and methods, kits and compositions related thereto.


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