The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 24, 2017

Filed:

Aug. 04, 2016
Applicants:

Respivert Limited, High Wycombe, Buckinghamshire, GB;

Topivert Pharma Limited, London, GB;

Inventors:

Matthew Colin Thor Fyfe, London, GB;

Michael Knaggs, Burton-on-Trent, GB;

Premji Meghani, Nottingham, GB;

Stephen Malcolm Thom, Nottingham, GB;

Assignees:

Respivert Limited, High Wycombe, Buckinghamshire, GB;

Topivert Pharma Limited, London, GB;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07F 9/6558 (2006.01); C07F 9/6568 (2006.01); A61K 31/675 (2006.01); A61K 31/695 (2006.01); C07D 213/68 (2006.01); C07D 231/14 (2006.01); C07D 239/22 (2006.01); C07F 7/08 (2006.01); C07F 9/28 (2006.01); C07F 9/30 (2006.01); C07F 9/6512 (2006.01); C07F 9/6503 (2006.01);
U.S. Cl.
CPC ...
C07F 9/65583 (2013.01); A61K 31/675 (2013.01); A61K 31/695 (2013.01); C07D 213/68 (2013.01); C07D 231/14 (2013.01); C07D 239/22 (2013.01); C07F 7/082 (2013.01); C07F 9/28 (2013.01); C07F 9/304 (2013.01); C07F 9/65685 (2013.01); C07F 9/6512 (2013.01); C07F 9/65031 (2013.01);
Abstract

There are provided compounds of formula I, wherein Rto R, X, X, Ar, L, A, A, E and G have meanings given in the description, which compounds have antiinflammatory activity (e.g. through inhibition of one or more of members of: the family of p38 mitogen-activated protein kinase enzymes; Syk kinase; and members of the Src family of tyrosine kinases) and have use in therapy, including in pharmaceutical combinations, especially in the treatment of inflammatory diseases, including inflammatory diseases of the lung, eye and intestines.


Find Patent Forward Citations

Loading…