The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 24, 2017
Filed:
Sep. 01, 2015
Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, CN;
Fudan University, Shanghai, CN;
Jingkang Shen, Shanghai, CN;
Ke Yu, Shanghai, CN;
Tao Meng, Shanghai, CN;
Lanping Ma, Shanghai, CN;
Arie Zask, Shanghai, CN;
Lanfang Meng, Shanghai, CN;
Xin Wang, Shanghai, CN;
Yiyi Chen, Shanghai, CN;
Abstract
The present invention belongs to the field of pharmaceutical Chemistry. In particular, the present invention relates to a pyridopyrimidine or pyrimidopyrimidine compound as represented by general formula (I), or an isomer thereof or a pharmaceutically acceptable salt, ester, prodrug or solvate thereof, a preparation method, a pharmaceutical composition and uses thereof in preparing a mTOR inhibitor. As a mTOR inhibitor, the compound or the pharmaceutical composition thereof can be used for treating a disease or condition due to PI3K-AKT-mTOR signalling pathway malfunction.