The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 24, 2017

Filed:

Mar. 13, 2014
Applicant:

Abbvie Inc., North Chicago, IL (US);

Inventors:

Yunsong Tong, Libertyville, IL (US);

Milan Bruncko, Green Oaks, IL (US);

Richard F. Clark, Gurnee, IL (US);

Michael Curtin, Pleasant Prairie, WI (US);

Alan S. Florjancic, Kenosha, WI (US);

Robin R. Frey, Libertyville, IL (US);

Jianchun Gong, Deefield, IL (US);

Todd M. Hansen, Grayslake, IL (US);

Zhiqin Ji, Libertyville, IL (US);

Chunqiu Lai, Libertyville, IL (US);

Anthony Mastracchio, Vernon Hills, IL (US);

Michael Michaelides, Libertyville, IL (US);

Juliem Miyashiro, Morton Grove, IL (US);

Roberto M. Risi, Kenosha, WI (US);

Xiaohong Song, Grayslake, IL (US);

Zhi-fu Tao, Vernon Hills, IL (US);

Keith W. Woods, Lincolnshire, IL (US);

Guidong Zhu, Gurnee, IL (US);

Thomas Penning, Elmhurst, IL (US);

Andrew Souers, Libertyville, IL (US);

Rajeev Goswami, Dehradun, IN;

Omprakash Reddy Iguturi, Guntur, IN;

Madhu Babu Dabbeeru, Srikakulam, IN;

Assignee:

AbbVie Inc., North Chicago, IL (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 401/02 (2006.01); C07D 401/10 (2006.01); A61K 31/437 (2006.01); A61K 31/4353 (2006.01); C07D 471/04 (2006.01); A61K 45/06 (2006.01); A61K 31/444 (2006.01); A61K 31/4545 (2006.01); A61K 31/497 (2006.01); A61K 31/5377 (2006.01);
U.S. Cl.
CPC ...
C07D 471/04 (2013.01); A61K 31/437 (2013.01); A61K 31/444 (2013.01); A61K 31/4545 (2013.01); A61K 31/497 (2013.01); A61K 31/5377 (2013.01); A61K 45/06 (2013.01);
Abstract

Disclosed are compounds of Formula (IIa), wherein R, R, R, R, R, R, R, and Rare as defined in the specification, and pharmaceutically acceptable salts thereof. The compounds may be used as agents in the treatment of diseases, including cancer. Also provided are pharmaceutical compositions comprising one or more compounds of Formula (IIa).


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