The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 24, 2017

Filed:

Nov. 24, 2015
Applicant:

Reata Pharmaceuticals, Inc., Irving, TX (US);

Inventors:

Eric Anderson, Southlake, TX (US);

Gary L. Bolton, Ann Arbor, MI (US);

Deborah A. Ferguson, Branchburg, NJ (US);

Xin Jiang, Coppell, TX (US);

Robert M. Kral, Jr., Grapevine, TX (US);

Patrick M. O'Brien, Stockbridge, MI (US);

Melean Visnick, Irving, TX (US);

Assignee:

REATA PHARMACEUTICALS, INC., Irving, TX (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/277 (2006.01); C07C 255/46 (2006.01); C07D 311/74 (2006.01); C07D 317/26 (2006.01); C07D 493/10 (2006.01); C07F 7/18 (2006.01); C07J 21/00 (2006.01); C07J 41/00 (2006.01); C07J 53/00 (2006.01); C07J 71/00 (2006.01);
U.S. Cl.
CPC ...
C07C 255/46 (2013.01); C07D 311/74 (2013.01); C07D 317/26 (2013.01); C07D 493/10 (2013.01); C07F 7/1856 (2013.01); C07J 21/003 (2013.01); C07J 41/0055 (2013.01); C07J 41/0094 (2013.01); C07J 53/001 (2013.01); C07J 71/0005 (2013.01); C07C 2601/16 (2017.05);
Abstract

This invention provides novel compounds comprising the following anti-inflammatory pharmacore: wherein X, Rand Rare defined herein. Also provided are pharmaceutical compositions, kits and articles of manufacture comprising such compounds, methods and intermediates useful for making the compounds, and methods of using the compounds and compositions.


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