The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 24, 2017

Filed:

Aug. 20, 2015
Applicant:

Professional Compounding Centers of America (Pcca), Houston, TX (US);

Inventors:

Chris V. Simmons, Sugar Land, TX (US);

Daniel Banov, Sugar Land, TX (US);

Assignee:
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 36/00 (2006.01); A61K 47/44 (2017.01); A61K 9/00 (2006.01); A61K 45/06 (2006.01); A61K 36/48 (2006.01); A61K 47/34 (2017.01); A61K 31/685 (2006.01); A61K 31/695 (2006.01); A61K 36/889 (2006.01); A61K 36/47 (2006.01);
U.S. Cl.
CPC ...
A61K 47/44 (2013.01); A61K 9/0046 (2013.01); A61K 31/685 (2013.01); A61K 31/695 (2013.01); A61K 36/47 (2013.01); A61K 36/48 (2013.01); A61K 36/889 (2013.01); A61K 45/06 (2013.01); A61K 47/34 (2013.01);
Abstract

The present disclosure relates to pharmaceutical compositions with increased skin permeability for treating ear disease in mammals. Disclosed pharmaceutical compositions are prepared as topical gels or as transdermal gels. The pharmaceutical compositions reduce ear inflammation and irritation produced by ear diseases or injuries (e.g., cauliflower ear, chronic otitis, and the like). The pharmaceutical compositions include a synergistic combination of pracaxi oil and seje oil. Additionally, the pharmaceutical compositions include phosphatidylcholine as a permeation enhancer. The combination of aforementioned natural components exhibits enhanced healing properties, thereby providing organic acids with antioxidant, antibacterial, and antifungal properties. The synergistic combination of pracaxi and seje oil increases the skin permeability to active pharmaceutical ingredients (APIs), thereby passing through the stratum corneum and reaching the target area; therefore, the dosage and time of treatment is significantly reduced.


Find Patent Forward Citations

Loading…