The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 24, 2017
Filed:
Feb. 11, 2015
Applicant:
Academia Sinica, Taipei, TW;
Inventors:
Assignee:
Academia Sinica, Taipei, TW;
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 39/145 (2006.01); C12N 7/01 (2006.01); A61P 31/16 (2006.01); A61K 39/42 (2006.01); C12N 15/44 (2006.01); A61K 39/215 (2006.01); C07K 14/005 (2006.01); A61K 39/12 (2006.01); C07K 16/10 (2006.01); G01N 33/569 (2006.01); A61K 39/00 (2006.01);
U.S. Cl.
CPC ...
A61K 39/145 (2013.01); A61K 39/12 (2013.01); A61K 39/215 (2013.01); C07K 14/005 (2013.01); C07K 16/1018 (2013.01); G01N 33/56983 (2013.01); A61K 2039/5258 (2013.01); C12N 2760/16034 (2013.01); C12N 2760/16122 (2013.01); C12N 2760/16123 (2013.01); C12N 2760/16134 (2013.01); C12N 2770/20022 (2013.01); C12N 2770/20023 (2013.01); C12N 2770/20034 (2013.01); C12N 2830/006 (2013.01); G01N 2333/11 (2013.01); G01N 2469/10 (2013.01); G01N 2469/20 (2013.01);
Abstract
Virus-like particles (VLPs) of mammalian-hosted viruses, such as SARS-CoV and influenza viruses, have been recombinantly produced from Vero cells. The VLPs closely emulate the exterior of authentic virus particles and are highly immunogenic. They can elicit not only humoral but also cellular immune responses in a mammal. Compositions and methods related to the VLPs are also described.