The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 24, 2017
Filed:
Dec. 28, 2015
Applicant:
Children's National Medical Center, Washington, DC (US);
Inventors:
Anthony Sandler, Bethesda, MD (US);
Lina Chakrabarti, Silver Spring, MD (US);
Assignee:
Children's National Medical Center, Washington, DC (US);
Primary Examiner:
Int. Cl.
CPC ...
A61K 39/00 (2006.01); A61K 39/395 (2006.01); C12N 5/09 (2010.01); C07K 14/47 (2006.01);
U.S. Cl.
CPC ...
A61K 39/0011 (2013.01); C07K 14/4702 (2013.01); C12N 5/0693 (2013.01); A61K 39/3955 (2013.01); A61K 2039/505 (2013.01); A61K 2039/5152 (2013.01); C12N 2501/60 (2013.01); C12N 2510/00 (2013.01);
Abstract
ID Protein targeted cancer immunotherapy. The invention provides a cell-based attenuated live tumor cell vaccine that safely produces broad cellular tumor-specific immunity, protects against tumor formation in prophylactic tumor models, and in combination with the clinically relevant immune modulator s such as antibodies to CTLA-4 or antibodies to PD-L1 can destroy established tumors in mammals.