The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 24, 2017
Filed:
Sep. 14, 2016
Applicant:
Index Pharmaceuticals Ab, Stockholm, SE;
Inventors:
Charlotte Admyre, Vendelsö, SE;
Arezou Zargari, Solna, SE;
Oliver Von Stein, Upplands Väsby, SE;
Petra Von Stein, Upplands Väsby, SE;
Assignee:
INDEX PHARMACEUTICALS AB, Stockholm, SE;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 48/00 (2006.01); A61K 31/713 (2006.01); A61K 39/00 (2006.01); C12N 15/117 (2010.01); A61K 45/06 (2006.01);
U.S. Cl.
CPC ...
A61K 31/713 (2013.01); A61K 39/0005 (2013.01); A61K 45/06 (2013.01); C12N 15/117 (2013.01); C12N 2310/17 (2013.01); C12N 2310/315 (2013.01); C12N 2320/31 (2013.01);
Abstract
A method of treating chronic active ulcerative colitis in a subject that is refractory or responds insufficiently or is intolerant to anti-inflammatory therapy, comprises administering to a patient in need thereof an effective exposure of an oligonucleotide comprising the sequence 5'-GGAACAGTTCGTCCATGGC-3′ (SEQ ID NO.2), wherein at least one CG dinucleotide is unmethylated. The oligonucleotide is not administered with corticosteroids or glucocorticosteroids.