The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 24, 2017
Filed:
Nov. 02, 2015
Nanocarrier Co., Ltd., Kashiwa, Chiba, JP;
Atsushi Ishii, Kashiwa, JP;
Yasuki Kato, Kashiwa, JP;
Nanocarrier Co., Ltd., Kashiwa, Chiba, JP;
Abstract
The present invention provides a particulate pharmaceutical composition which has improved drug encapsulation stability and is suitable for a drug delivery system. The particulate pharmaceutical compositioncontains: a plurality of block copolymer unitarranged radially, each of which has a hydrophobic polymer-chain segment, which is arranged radially inside, and a hydrophilic polymer-chain segment, which is arranged radially outside; a drug, which includes a biomacromolecule; and a charged lipid, which has an electrical charge opposite to that of the drug; wherein the charged lipidis being attracted to the hydrophobic polymer-chain segment, and the drugis positioned radially inside the hydrophobic polymer-chain segment. The pharmaceutical compositioncan effectively prevent the drugfrom disengaging from the particle.