The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 24, 2017

Filed:

Jan. 06, 2017
Applicant:

Pac-dent International Inc., Brea, CA (US);

Inventors:

Susan Jiao, Irvine, CA (US);

Daniel Wang, Brea, CA (US);

Bo Tao, Chino, CA (US);

Xiao Yang, La Habra, CA (US);

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 8/86 (2006.01); A61K 8/02 (2006.01); A61Q 11/00 (2006.01); A61K 8/24 (2006.01); A61K 8/81 (2006.01); A61K 8/73 (2006.01); C08J 3/12 (2006.01); C08J 3/14 (2006.01);
U.S. Cl.
CPC ...
A61K 8/0291 (2013.01); A61K 8/022 (2013.01); A61K 8/24 (2013.01); A61K 8/736 (2013.01); A61K 8/8164 (2013.01); A61K 8/86 (2013.01); A61Q 11/00 (2013.01); C08J 3/12 (2013.01); C08J 3/14 (2013.01); A61K 2800/48 (2013.01); A61K 2800/524 (2013.01); A61K 2800/5424 (2013.01); A61K 2800/5426 (2013.01); C08J 2305/08 (2013.01); C08J 2325/08 (2013.01); C08J 2335/00 (2013.01); C08J 2371/02 (2013.01);
Abstract

The invention relates to nano-sized complexes formed by associating amorphous calcium phosphate (ACP) and/or amorphous calcium fluoride phosphate (ACFP) with an amphiphilic polymer surfactant. The amphiphilic polymer surfactants can form nano-sized assemblies in aqueous solution, serving as a nano dispersant preventing ACP and/or ACFP from aggregation, and as a nano carrier associating or attaching ACP and/or ACFP, stabilizing ACP and/or ACFP against the conversion to a crystalline form as well, thus maintaining calcium and phosphate/and fluoride ions in a bioavailable state for dental re-mineralization and prevention of dental caries, dental calculus and dental hyper-sensitivity. A method for the nano-sized complex preparation and compositions comprising the nano-sized complexes are also provided.


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