The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 24, 2017

Filed:

Sep. 29, 2015
Applicant:

University of Maryland, College Park, College Park, MD (US);

Inventors:

Laura Bracaglia, Herndon, VA (US);

Poonam Sharma, Conshohocken, PA (US);

John Patrick Fisher, Kensington, MD (US);

Assignee:

University Of Maryland, College Park, College Park, MD (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61F 13/00 (2006.01); A61F 2/00 (2006.01); A61F 13/02 (2006.01); A61K 38/18 (2006.01); A61F 2/02 (2006.01); A61L 27/54 (2006.01); A61L 27/56 (2006.01); A61L 27/48 (2006.01);
U.S. Cl.
CPC ...
A61F 2/02 (2013.01); A61L 27/48 (2013.01); A61L 27/54 (2013.01); A61L 27/56 (2013.01); A61F 2210/0004 (2013.01); A61F 2210/0076 (2013.01); A61L 2420/02 (2013.01); A61L 2420/08 (2013.01); A61L 2430/20 (2013.01);
Abstract

Provided are hybrid biomaterials comprising one or more layers of cross-linked poly(propylene fumarate) and/or cross-linked copolymer comprising a plurality of cross-linked propylene fumarate moieties. The layers may further comprise a plurality of microparticles, a plurality of micropores, or both a plurality of microparticles and a plurality of micropores encapsulated within the cross-linked poly(propylene fumarate) and/or cross-linked copolymer comprising a plurality of cross-linked propylene fumarate moieties. One of the layers is disposed on a compliant matrix dense tissue substrate (e.g., a pericardium tissue substrate). The hybrid biomaterials can be used, for example, in method of repairing tissue defects.


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