The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 17, 2017

Filed:

Dec. 26, 2012
Applicants:

International Business Machines Corporation, Armonk, NY (US);

University of Melbourne, Parkville, Victoria, AU;

Florey Neuroscience Institute, Parkville, Victoria, AU;

Inventors:

Matthew Downton, Victoria, AU;

Natalie Gunn, Victoria, AU;

Stefan Harrer, Hampton, AU;

Priscilla Rogers, Victoria, AU;

John Wagner, North Melbourne, AU;

Ross Bathgate, Victoria, AU;

Daniel Scott, Victoria, AU;

Stan Skafidas, Victoria, AU;

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
G01N 33/68 (2006.01); C07K 14/72 (2006.01);
U.S. Cl.
CPC ...
G01N 33/6872 (2013.01); C07K 14/723 (2013.01); G01N 2333/726 (2013.01);
Abstract

A mechanism is provided for utilizing a nanodevice to distinguish molecules with different structure. The molecules translocate through or across a nanochannel filled with a electrolyte solution. An electrical signal through the nanochannel is measured for every translocation event. Inner surfaces of the nanochannel include a functional layer, which is a coating to functionalize the nanochannel, in which the functional layer is configured to interact with predetermined ones of the molecules during translocation events. It is determined that a combination of at least two different molecules is formed based on predetermined ones of the molecules interacting with the functional layer to change the electrical signal and/or change a translocation time for the translocation event.


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