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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 9790524 B1

PDFFull Text
Expired
Date of Patent:
Oct. 17, 2017

Filed:

Apr. 17, 2014

Designer cells for enantioselective reduction of ketones and use thereof in efficient production of enantioenriched alcohols

Applicant:

Council of Scientific & Industrial Research, New Delhi, IN;

Inventors:

Gautam Srivastava, Chandigarh, IN;

Suneet Kaur, Chandigarh, IN;

Ravinder Singh Jolly, Chandigarh, IN;

Assignee:

COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH, New Delhi, IN;

Attorney:

Workman Nydegger

Primary Examiner:

Tekchand Saidha

Assistant Examiner:

Md Younus Meah

Int. Cl.
CPC ...
C12N 9/04 (2006.01); C12N 1/20 (2006.01); C12N 15/00 (2006.01); C12P 7/04 (2006.01); C12P 7/62 (2006.01); C12P 41/00 (2006.01); C12P 7/22 (2006.01); C12P 13/00 (2006.01);
U.S. Cl.
CPC ...
C12P 7/62 (2013.01); C12N 9/0006 (2013.01); C12P 7/22 (2013.01); C12P 13/008 (2013.01); C12P 41/002 (2013.01); C12Y 101/01184 (2013.01); C12Y 101/01047 (2013.01);
Abstract

The present invention is to provide a preparation of variant recombinant whole cell biocatalysts, referred herein as 'designer cells' having significantly enhanced carbonyl reductase activity for use in the efficient production of variant industrially important enantiomerically enriched alcohols. More specifically, the alcohol is optically pure ethyl (S)-4-chloro-3-hydroxybutyrate, which is useful as chiral building block and an intermediate for the production of hydroxymethylglutaryl-CoA (HMG-CoA) reductase inhibitors.

Find Patent Forward Citations

Srivastava, Gautam. (2017). Designer cells for enantioselective reduction of ketones and use thereof in efficient production of enantioenriched alcohols (U.S. Patent No. 9790524). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/9790524

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