The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 17, 2017
Filed:
Jul. 11, 2016
Benitec Biopharma Limited, Balmain, New South Wales, AU;
Michael Wayne Graham, Jindalee, AU;
Peter French, Balmain, AU;
York YuanYuan Zhu, Palo Alto, CA (US);
YiXiang Lu, Nantong, CN;
TieJun Li, Nantong, CN;
YunCheng Sun, Nantong, CN;
XiaoJun Tang, Nantong, CN;
Li Shan, Laval, CA;
BENITEC BIOPHARMA LIMITED, Balmain, New South Wales, AU;
Abstract
This invention is directed to a RNA interference (RNAi) agent and the use of that RNAi agent to treat hepatitis B infection in individuals, as well as pharmaceutical compositions containing the RNAi agents of the invention. The RNAi agents, or constructs for expressing them are utilized to inhibit expression of at least one Hepatitis B virus (HBV) gene, where the agent comprises an effector sequence complementary to or substantially complementary to a predicted sequence transcribed from a target region. In some forms of the invention, the agent has more than one effector sequence. Multiple effectors may target the same region of an HBV gene, different (possibly overlapping) regions of the same gene and/or different HBV genes.