The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 17, 2017

Filed:

Oct. 27, 2015
Applicant:

Lipoxen Technologies Limited, London, GB;

Inventors:

Sanjay Jain, London, GB;

Ioannis Papaioannou, London, GB;

Peter Laing, London, GB;

Assignee:
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
B01D 15/34 (2006.01); B01D 15/36 (2006.01); C08B 37/00 (2006.01); C07K 14/61 (2006.01); C07K 1/18 (2006.01); A61K 47/48 (2006.01); B01D 24/02 (2006.01); B01D 15/42 (2006.01);
U.S. Cl.
CPC ...
C08B 37/0006 (2013.01); A61K 47/4823 (2013.01); B01D 15/361 (2013.01); B01D 15/362 (2013.01); B01D 15/363 (2013.01); B01D 15/424 (2013.01); C07K 1/18 (2013.01); C07K 14/61 (2013.01); C08B 37/0003 (2013.01); B01D 15/426 (2013.01);
Abstract

Polydisperse and charged polysaccharides are fractionated into low polydispersity fractions (preferably having pd<1.1), each containing species within a narrow range of molecular weights. An aqueous solution of the polydisperse polysaccharides is contacted with an ion exchange resin in a column and the polysaccharides are subjected to selective elution by aqueous elution buffer. The selective elution consists of at least 3 sequential elution buffers having different and constant ionic strength and/or pH and in which the subsequent buffers have ionic strength and/or pH than those of the preceding step. The new preparations are particularly suitable for the production of PSA-derivatised therapeutic agents intended for use in humans and animals.


Find Patent Forward Citations

Loading…