The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 17, 2017
Filed:
Aug. 06, 2014
Applicant:
Imago Biosciences Inc., San Carlos, CA (US);
Inventors:
John M. McCall, Boca Grande, FL (US);
Hugh Young Rienhoff, Jr., San Carlos, CA (US);
Michael Clare, Skokie, IL (US);
Assignee:
Imago Biosciences, Inc., San Carlos, CA (US);
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C07D 295/192 (2006.01); C07D 237/22 (2006.01); C07D 213/81 (2006.01); C07D 233/90 (2006.01); C07D 295/185 (2006.01); C07D 295/26 (2006.01); A61K 31/166 (2006.01); A61K 31/40 (2006.01); A61K 31/4453 (2006.01); A61K 31/454 (2006.01); A61K 31/4545 (2006.01); A61K 31/47 (2006.01); A61K 31/495 (2006.01); A61K 31/5375 (2006.01); A61K 31/54 (2006.01); C07D 215/14 (2006.01); C07C 237/22 (2006.01);
U.S. Cl.
CPC ...
C07D 295/192 (2013.01); A61K 31/166 (2013.01); A61K 31/40 (2013.01); A61K 31/4453 (2013.01); A61K 31/454 (2013.01); A61K 31/4545 (2013.01); A61K 31/47 (2013.01); A61K 31/495 (2013.01); A61K 31/5375 (2013.01); A61K 31/54 (2013.01); C07C 237/22 (2013.01); C07D 213/81 (2013.01); C07D 215/14 (2013.01); C07D 233/90 (2013.01); C07D 295/185 (2013.01); C07D 295/26 (2013.01); C07C 2601/02 (2017.05);
Abstract
Disclosed herein are new compounds and compositions and their application as pharmaceuticals for the treatment of diseases. Methods of inhibition of KDMIA, methods of increasing gamma globin gene expression, and methods to induce differentiation of cancer cells in a human or animal subject are also provided for the treatment of diseases such as acute myelogenous leukemia.