The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 17, 2017

Filed:

Apr. 17, 2014
Applicant:

President and Fellows of Harvard College, Cambridge, MA (US);

Inventors:

Darren Roy Link, Lexington, MA (US);

David A. Weitz, Bolton, MA (US);

Galder Cristobal-Azkarate, Bordeaux, FR;

Zhengdong Cheng, College Station, TX (US);

Keunho Ahn, San Diego, CA (US);

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
B01L 3/00 (2006.01); B01F 5/06 (2006.01); B01F 13/00 (2006.01); B01J 19/00 (2006.01); G01N 15/14 (2006.01); B01F 5/02 (2006.01);
U.S. Cl.
CPC ...
B01L 3/5027 (2013.01); B01F 5/0646 (2013.01); B01F 5/0655 (2013.01); B01F 5/0682 (2013.01); B01F 5/0689 (2013.01); B01F 13/0071 (2013.01); B01F 13/0074 (2013.01); B01F 13/0076 (2013.01); B01J 19/0093 (2013.01); B01L 3/502784 (2013.01); G01N 15/14 (2013.01); B01F 5/0256 (2013.01); B01J 2219/00783 (2013.01); B01J 2219/00862 (2013.01); B01L 2200/0673 (2013.01); B01L 2300/0864 (2013.01); B01L 2300/0867 (2013.01); B01L 2400/0415 (2013.01); B01L 2400/0439 (2013.01); B01L 2400/0487 (2013.01); Y10S 436/807 (2013.01); Y10T 436/118339 (2015.01); Y10T 436/2525 (2015.01); Y10T 436/2575 (2015.01);
Abstract

Various aspects of the present invention relate to the control and manipulation of fluidic species, for example, in microfluidic systems. In one aspect, the invention relates to systems and methods for making droplets of fluid surrounded by a liquid, using, for example, electric fields, mechanical alterations, the addition of an intervening fluid, etc. In another aspect, the invention relates to systems and methods for dividing a fluidic droplet into two droplets, for example, through charge and/or dipole interactions with an electric field. The invention also relates to systems and methods for fusing droplets, according to another aspect of the invention, for example, through charge and/or dipole interactions. Another aspect of the invention provides the ability to determine droplets, or a component thereof, for example, using fluorescence and/or other optical techniques (e.g., microscopy), or electric sensing techniques such as dielectric sensing.


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