The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 17, 2017
Filed:
Sep. 18, 2014
Institute of Nuclear Energy Research Atomic Energy Council, Executive Yuan, Taoyuan County, TW;
National Yang-ming University, Taipei, TW;
Hsin-Ell Wang, Taoyuan County, TW;
Chien-Chung Hsia, Taoyuan County, TW;
Mao-Chi Weng, Taoyuan County, TW;
Kun-Liang Lin, Taoyuan County, TW;
Hao-Wen Kao, Taoyuan County, TW;
Chao-Cheng Chen, Taoyuan County, TW;
Kwan-Hwa Chi, Taoyuan County, TW;
Der-Chi Tien, Taoyuan County, TW;
Wuu-Jyh Lin, Taoyuan County, TW;
INSTITUTE OF NUCLEAR ENERGY RESEARCH ATOMIC ENERGY COUNCIL, EXECUTIVE YUAN, Taoyuan County, TW;
NATIONAL YANG-MING UNIVERSITY, Taipei, TW;
Abstract
The present invention is related to a radiolabeled active targeting pharmaceutical composition, including: a bioconjugate and a radionuclide, wherein the bioconjugate includes a biomolecule and a metal nanoparticle, wherein the biomolecule has an affinity for receptors on the surface of a cell membrane and is selected from the group consisting of a peptide and a protein. The present invention further provides a method for evaluating a thermal adjuvant therapy for tumors and a kit thereof. The above-mentioned pharmaceutical composition is applied to evaluate a tumor accumulation time, so as to establish the optimal policy for a radiofrequency- or laser-induced thermal adjuvant therapy for tumors.