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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 9789187 B1

PDFFull Text
Date of Patent:
Oct. 17, 2017

Filed:

Feb. 08, 2010

Stable pharmaceutical composition for atherosclerosis

Applicants:

Bakulesh Mafatlal Khamar, Ahmedabad, IN;

Kumud Kumar Padhee, Ahmedabad, IN;

Nilamkumari Somalal Patel, Ahmedabad, IN;

Sunil Chowdary Koduri, Ahmedabad, IN;

Amit Mukharya, Ahmedabad, IN;

Indravadan Ambalal Modi, Ahmedabad, IN;

Rajiv Indravadan Modi, Ahmedabad, IN;

Inventors:

Bakulesh Mafatlal Khamar, Ahmedabad, IN;

Kumud Kumar Padhee, Ahmedabad, IN;

Nilamkumari Somalal Patel, Ahmedabad, IN;

Sunil Chowdary Koduri, Ahmedabad, IN;

Amit Mukharya, Ahmedabad, IN;

Indravadan Ambalal Modi, Ahmedabad, IN;

Rajiv Indravadan Modi, Ahmedabad, IN;

Assignee:

Cadila Pharmaceuticals Limited, Ahmedabad, IN;

Attorney:

Pepper Hamilton LLP

Primary Examiner:

Rachael Bredefeld

Int. Cl.
CPC ...
A61K 45/06 (2006.01); A61K 31/445 (2006.01); A61K 31/00 (2006.01); A61K 9/20 (2006.01); A61K 9/16 (2006.01); A61K 9/24 (2006.01); A61K 9/28 (2006.01); A61K 9/48 (2006.01); A61K 9/50 (2006.01);
U.S. Cl.
CPC ...
A61K 45/06 (2013.01); A61K 9/1623 (2013.01); A61K 9/1652 (2013.01); A61K 9/209 (2013.01); A61K 9/2054 (2013.01); A61K 9/2077 (2013.01); A61K 9/2846 (2013.01); A61K 9/2866 (2013.01); A61K 9/2886 (2013.01); A61K 9/4808 (2013.01); A61K 9/4866 (2013.01); A61K 9/5084 (2013.01); A61K 31/00 (2013.01); A61K 31/445 (2013.01);
Abstract

The present invention relates to a stable solid oral pharmaceutical multi-component composition comprising combination of blood pressure lowering drugs with lipid lowering agent/s and optionally a platelet aggregation inhibitor in a single dosage form. The blood pressure lowering agents are selected from β-adrenergic receptor blocking agent, ACE inhibitor and diuretic. The lipid lowering agent is selected from HMG Co-enzyme-A reductase inhibitor. The pharmaceutical composition made as per present invention a) overcomes any drug-drug interactions, b) exhibits pharmacokinetic and pharmacodynamic profile of individual therapeutic agent, c) has minimal side effects. The invention provides multi-component composition (MCC) to increase adherences to therapy. The MCC as per present invention provides compositions that maintain activity of all active ingredients without significant increase in adverse event profile. The present invention further relates to a method of preparing the said pharmaceutical composition.

Find Patent Forward Citations

Khamar, Bakulesh. (2017). Stable pharmaceutical composition for atherosclerosis (U.S. Patent No. 9789187). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/9789187

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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