The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 17, 2017

Filed:

Dec. 22, 2015
Applicant:

Epimmune Inc., San Diego, CA (US);

Inventors:

Florence Dal Degan, Cheney, FR;

Mark J. Newman, Duluth, GA (US);

Jeffery L. Alexander, San Diego, CA (US);

Scott Southwood, Santee, CA (US);

Assignee:

EPIMMUNE INC., San Diego, CA (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07K 7/08 (2006.01); C07K 19/00 (2006.01); A61K 39/00 (2006.01); A61K 39/39 (2006.01); C07K 14/74 (2006.01);
U.S. Cl.
CPC ...
A61K 39/39 (2013.01); C07K 7/08 (2013.01); A61K 2039/55516 (2013.01); C07K 2319/00 (2013.01);
Abstract

The present invention provides novel artificial oligopeptides capable of binding HLA Class II molecules encoded by several alleles. The oligopeptides include the sequence AXFVAAXTLXAXA (SEQ ID NO:1), wherein Xis H; Xis selected from the group consisting of F, N, Y and W; Xis H and Xis selected from the group consisting of A, D and E. The invention also relates to large peptides comprising the oligopeptides, polynucleotides encoding the oligopeptides and larger peptides, as well as to compositions comprising the oligopeptides, peptides or polynucleotides. Also disclosed are methods for inducing immune responses.


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