The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 17, 2017
Filed:
Nov. 07, 2014
Applicant:
Merck Patent Gmbh, Darmstadt, DE;
Inventors:
Andreas Nandy, Hamburg, DE;
Helmut Fiebig, Schwarzenbek, DE;
Oliver Cromwell, Suesel-Fassendorf, DE;
Assignee:
MERCK PATENT GMBH, Darmstadt, DE;
Primary Examiner:
Int. Cl.
CPC ...
A61K 39/35 (2006.01); C07K 14/415 (2006.01); A61K 39/00 (2006.01);
U.S. Cl.
CPC ...
A61K 39/35 (2013.01); C07K 14/415 (2013.01); A61K 39/00 (2013.01);
Abstract
The present invention relates to the provision of a DNA sequence of the major grass pollen allergen Lol p 4. The invention also encompasses fragments, new combinations of partial sequences and point mutants having a hypoallergenic action. The recombinant DNA molecules and the derived polypeptides, fragments, new combinations of partial sequences and variants can be utilized for the therapy of pollen-allergic diseases. The proteins prepared by recombinant methods can be employed for in vitro and in vivo diagnosis of pollen allergies.