The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 17, 2017

Filed:

Apr. 28, 2015
Applicant:

Bio-cancer Treatment International Limited, Shatin, New Territories, HK;

Inventors:

Gernot Schabbauer, Vienna, AT;

Stephen Bluml, Vienna, AT;

Emine Sahin-Heco, Vienna, AT;

Paul Cheng, Shatin, HK;

Li Chen, Shatin, HK;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 38/50 (2006.01); C12N 9/78 (2006.01); A61K 9/00 (2006.01); A61K 47/48 (2006.01);
U.S. Cl.
CPC ...
A61K 38/50 (2013.01); A61K 9/0019 (2013.01); A61K 47/48215 (2013.01); C12N 9/78 (2013.01); C12Y 305/03001 (2013.01);
Abstract

Methods and compositions comprising recombinant Arginase I proteins which are capable of depleting the plasma arginine levels in a subject are disclosed. The methods and compositions can be used to modulate the activity of the immune system in a subject. Modulation of the immune system is useful in the treatment of immune disorders and in preventing rejection of a transplanted organ, tissue, or cell. The methods and compositions can also be used to treat a bone condition of a subject.


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