The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 17, 2017
Filed:
Dec. 17, 2012
Nuria Izquierdo Useros, Barcelona, ES;
Hans-georg Krauesslich, Heidelberg, DE;
Maier Lorizate, Portugalete, ES;
Javier Martinez Picado, Vilassar del Mar, ES;
Nuria Izquierdo Useros, Barcelona, ES;
Hans-Georg Krauesslich, Heidelberg, DE;
Maier Lorizate, Portugalete, ES;
Javier Martinez Picado, Vilassar del Mar, ES;
LABORATORIOS DEL DR. ESTEVE, S.A., Barcelona, ES;
FUNDACIÓ PRIVADA INSTITUT DE RECERCA DE LA SIDA—CAIXA, Badalona, ES;
INSTITUCIÓ CATALANA DE RECERCA I ESTUDIS AVANÇATS, Barcelona, ES;
RUPRECHT-KARLS-UNIVERSITAET HEIDELBERG, Heidelberg, DE;
Abstract
The present invention refers to methods and compositions to prevent viral entry into cells expressing the CD169/sialoadhesin surface receptor by inhibiting the coupling of the sialyllactose molecule contained in the viral membrane gangliosides to the CD 169/sialoadhesin receptor. The invention also pertains to vaccine compositions based on dendritic cells loaded with an antigen of interest whereby the vaccine is provided together with a composition capable of preventing viral entry into cells expressing the CD169/sialoadhesin. Moreover, the invention relates to diagnostic and therapeutic compositions that can be specifically delivered to enveloped virions wherein the diagnostic/therapeutic agent is coupled to CD169/sialoadhesin.