The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 10, 2017

Filed:

Apr. 30, 2015
Applicant:

GE Healthcare Bio-sciences Corp., Piscataway, NJ (US);

Inventors:

Brion Daryl Sarachan, Niskayuna, NY (US);

Alberto Santamaria-Pang, Niscayuna, NY (US);

Yousef Al-Kofahi, Niscayuna, NY (US);

Edward John Moler, Aliso Viejo, CA (US);

Raghav Krishna Padmanabhan, Aliso Viejo, CA (US);

Qing Li, Niskayuna, NY (US);

Assignee:

GE HEALTHCARE BIO-SCIENCES CORP., Piscataway, NJ (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
G06K 9/00 (2006.01); G06K 9/03 (2006.01); G01N 1/30 (2006.01); G06F 19/00 (2011.01);
U.S. Cl.
CPC ...
G06K 9/036 (2013.01); G01N 1/30 (2013.01); G06F 19/366 (2013.01); G06K 9/0014 (2013.01);
Abstract

The disclosed subject matter relates to an automated determination the stain quality and segmentation quality of a tissue sample. By way of example, separate image data is acquired of an unstained form of a biological specimen, the biological specimen stained with a nuclei marker and the biological specimen stained with a segmentation marker. A correlation map (Cr) from the separate image data and a ridgeness map (Pr) from the image data of the biological specimen stained with a segmentation marker are each determined. A staining quality score and segmentation quality score are then determined from the correlation map (Cr) and the ridgeness map (Pr).


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