The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 10, 2017

Filed:

Apr. 18, 2016
Applicant:

Bio-rad Laboratories, Inc., Hercules, CA (US);

Inventors:

Fredrik Höök, Alingsås, SE;

Magnus Brändén, Göteborg, SE;

Seyed Tabaei, Göteborg, SE;

Assignee:

Bio-Rad Laboratories, Inc., Hercules, CA (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
G01N 21/41 (2006.01); G01N 21/552 (2014.01); G01N 33/68 (2006.01); G01N 33/543 (2006.01); G01N 33/50 (2006.01); G01N 33/92 (2006.01); G01N 21/21 (2006.01); G01N 21/25 (2006.01);
U.S. Cl.
CPC ...
G01N 33/68 (2013.01); G01N 21/41 (2013.01); G01N 21/553 (2013.01); G01N 33/50 (2013.01); G01N 33/5432 (2013.01); G01N 33/54353 (2013.01); G01N 33/54373 (2013.01); G01N 33/6872 (2013.01); G01N 33/92 (2013.01); G01N 21/211 (2013.01); G01N 2021/258 (2013.01); G01N 2333/43565 (2013.01); G01N 2500/00 (2013.01);
Abstract

The present invention provides a method for studying transport of an agent across a membrane comprising the steps a) providing at least one surface with a bilayer structure tethered to the surface, said bilayer structure comprising a detection volume, b) contacting the bilayer with at least one agent to be analyzed, and c) detecting a change in refractive index in the detection volume resulting from transportation of the agent across the membrane. Further there is provided a device comprising a) at least one surface, b) at least one bilayer structure tethered to the surface, and c) at least one sensor capable of detecting a change in refractive index in a detection volume, wherein the bilayer structure encloses a first volume of the detection volume and wherein the volume not enclosed by the bilayer structure but within the detection volume is a second volume and wherein the ratio between the first volume and second volume is above about 0.001.


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