The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 10, 2017
Filed:
Sep. 06, 2012
Yasuteru Urano, Tokyo, JP;
Tetsuo Nagano, Tokyo, JP;
Daisuke Asanuma, Tokyo, JP;
Kenzo Hirose, Tokyo, JP;
Shigeyuki Namiki, Tokyo, JP;
Yousuke Takaoka, Tokyo, JP;
Yasuteru Urano, Tokyo, JP;
Tetsuo Nagano, Tokyo, JP;
Daisuke Asanuma, Tokyo, JP;
Kenzo Hirose, Tokyo, JP;
Shigeyuki Namiki, Tokyo, JP;
Yousuke Takaoka, Tokyo, JP;
THE UNIVERSITY OF TOKYO, Tokyo, JP;
Abstract
Provided is a compound represented by formula (I), which can be used as a fluorescent probe that becomes highly fluorescent only in an intracellular acidic environment and can be adapted to the fluorescent imaging of an intracellular vesicle that is a microstructure. In the formula, Rand Rindependently represent a hydrogen atom, or an alkyl group which may be substituted (wherein Rand/or Rrepresents an alkyl group which may be substituted); R, R, R, R, Rand Rindependently represent a hydrogen atom, a halogen atom, or the like; X represents a functional group to which a labeling site or a target-accumulating site can be introduced, or the like; Y represents a halogen atom, an alkyl group which may be substituted, or the like; m represents an integer of 0 to 5; and n represents an integer of 0 to 5.