The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 10, 2017
Filed:
Jul. 30, 2012
Applicants:
Shin-ichiro Fujii, Yokohama, JP;
Kanako Shimizu, Yokohama, JP;
Jun Shinga, Yokohama, JP;
Inventors:
Assignee:
RIKEN, Saitama, JP;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 15/85 (2006.01); A61K 39/00 (2006.01); C07K 14/47 (2006.01); C07K 14/82 (2006.01);
U.S. Cl.
CPC ...
C12N 15/85 (2013.01); A61K 39/0011 (2013.01); C07K 14/4748 (2013.01); C07K 14/82 (2013.01); A61K 2039/5152 (2013.01); A61K 2039/5156 (2013.01); C07K 2319/00 (2013.01); C07K 2319/50 (2013.01);
Abstract
A cell of the present invention contains a nucleic acid construct encoding a WT1 gene product or a fragment of the WT1 gene product. The nucleic acid construct contains (i) a region encoding a desired fragment of the WT1 gene product and (ii) only AUG as a functional start codon. The present invention can provide a cell into which the nucleic acid construct is introduced so that an expression level of a WT1 gene product or a fragment of the WT1 gene product is remarkably enhanced.