The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 10, 2017
Filed:
Jun. 29, 2012
Applicants:
Ralf Mrowka, Jena, DE;
Gunter Wolf, Jena, DE;
Stefan Wolfl, Dossenheim, DE;
Xinlai Cheng, Kaiserslautern, DE;
Inventors:
Ralf Mrowka, Jena, DE;
Gunter Wolf, Jena, DE;
Stefan Wolfl, Dossenheim, DE;
Xinlai Cheng, Kaiserslautern, DE;
Assignees:
UNIVERSITATSKLINIKUM JENA, Jena, DE;
Other;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 5/02 (2006.01); C12N 5/074 (2010.01);
U.S. Cl.
CPC ...
C12N 5/0696 (2013.01); C12N 2501/603 (2013.01); C12N 2501/605 (2013.01); C12N 2501/999 (2013.01); C12N 2506/09 (2013.01); C12N 2506/11 (2013.01); C12N 2506/1315 (2013.01); C12N 2506/1323 (2013.01); C12N 2506/14 (2013.01); C12N 2506/25 (2013.01);
Abstract
The invention relates to a method for inducing pluripotent stem cells, wherein a mammalian cell is contacted with a compound characterized by a general formula 1 wherein Ris (CH)E, with E being CCH or CN and m being 0, 1, or 2, and Ris selected from F, CI, Br, ORand R, with Rbeing selected from H, (CHF)CHF, with n=0 or 1. The invention further relates to stem cells obtained by the method of the invention, and culture media comprising the compound of the invention.