The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 10, 2017
Filed:
Jan. 29, 2014
Applicant:
Cornell University, Ithaca, NY (US);
Inventor:
Pengbo Zhou, Princeton Junction, NJ (US);
Assignee:
Cornell University, Ithaca, NY (US);
Primary Examiner:
Int. Cl.
CPC ...
C07K 14/47 (2006.01); C12N 5/0789 (2010.01); A61K 35/28 (2015.01);
U.S. Cl.
CPC ...
C12N 5/0647 (2013.01); A61K 35/28 (2013.01); C07K 14/47 (2013.01); C07K 14/4702 (2013.01); C12N 2501/125 (2013.01); C12N 2501/145 (2013.01); C12N 2501/26 (2013.01); C12N 2501/60 (2013.01);
Abstract
The present disclosure relates to methods for expansion of stem cell populations using a polypeptide that enhances stem cell growth and proliferation. The present disclosure further relates to novel homeobox protein mutants (e.g., HOXA9 and HOXB4 mutant proteins) and the use thereof to expand certain stem cell populations. The present disclosure also provides methods for treating a subject in need of transplantation of stem cells.